NMATFBS

Database of transcription factor binding sites in non-model animals


Welcome to NMATFBS

The NMATFBS database contains transcription factor binding sites for ten common non-model animals, including pigs, cattle, sheep, and dogs. The database contains information on transcription factor binding sites, transcription factors, and corresponding target genes of 10 non-model animals. You can query by entering the species name, gene name, and transcription factor id.

Possible Application scenarios of NMATFBS

1. Hope to build a relevant regulatory network through data;
2. People who are interested in TF and its vital regulatory disorders;
3. People who are interested in the study of coregulation of transcription factor binding sites;
4. Individuals who wish to conduct computer analysis of the cis-regulatory components of animals provided by NMATFBS.

References

  1. Timothy L. Bailey and Charles Elkan, Fitting a mixture model by expectation maximization to discover motifs in biopolymers, Proceedings of the Second International Conference on Intelligent Systems for Molecular Biology. 1994, 28-36, AAAI Press.
  2. imothy L. Bailey and Philip Machanick, Inferring direct DNA binding from ChIP-seq, Nucleic Acids Research, 40:e128, 2012.
  3. Charles E. Grant, Timothy L. Bailey, and William Stafford Noble, FIMO: Scanning for occurrences of a given motif, Bioinformatics, 27(7):1017-1018, 2011.
  4. Xie GY, Xia M, Miao YR, Luo M, Zhang Q#, Guo AY#. FFLtool: A Web Server for Transcription Factor and miRNA Feed Forward Loop Analysis in Human. Bioinformatics. btz929. 2019 In Press
  5. Shobhit Gupta, JA Stamatoyannopolous, Timothy Bailey and William Stafford Noble, Quantifying similarity between motifs, Genome Biology, 8(2):R24, 2007.